BIOLOGICAL INDICATORS OF CHEMORESISTANCE: AN EX VIVO ANALYSIS OF γH2AX AND P53 EXPRESSION IN FELINE INJECTION-SITE SARCOMAS

Biological indicators of chemoresistance: an ex vivo analysis of γH2AX and p53 expression in feline injection-site sarcomas

Abstract Journal Background The response of soft tissue sarcomas to cytotoxic chemotherapy is inconsistent.Biomarkers of chemoresistance or chemosensitivity are needed in order to identify appropriate patients for treatment.Given that many chemotherapeutics kill cells through direct DNA interactions, we hypothesized that upregulation of DNA damage

read more

PHILIP GlASS: SCREEN MUSIC

Research is devoted to the music of contemporary composer Philip Glass, which he wrote specifically for the movies including feature and documentary films by American, British and Australian directors (M.Scorsese, E.Morris, S.Daldry, P.Weir etc.).It makes a connection of the Journal composition technologies between his filmmusic and his artmusic wr

read more

Identification and characterization of Brevibacillus halotolerans B-4359: a potential antagonistic bacterium against red pepper anthracnose in Korea

Our study aimed to identify potential biocontrol agents (BCAs) against major phytopathogens under in vitro conditions by screening the Freshwater Bioresources Culture Collection (FBCC), Korea.Of the identified 856 strains, only 65 exhibited antagonistic activity, among which only one representative isolation, Brevibacillus halotolerans B-4359 was s

read more


Tannic acid-functionalized 3D porous nanofiber sponge for antibiotic-free wound healing with enhanced hemostasis, antibacterial, and antioxidant properties

Abstract Developing an antibiotic-free wound dressing with effective hemostasis and antibacterial and antioxidant capacity is highly desirable.In this work, a three-dimensional (3D) chitosan/polyvinyl alcohol-tannic acid porous nanofiber sponge (3D-TA) was prepared via electrospinning.Compared with two-dimensional (2D) fiber membrane, the unique fl

read more